Targeting of High Peak Respiratory Exchange Ratio Is Safe and Enhances the Prognostic Power of Peak Oxygen Uptake for Heart Failure Patients

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Targeting of high peak respiratory exchange ratio is safe and enhances the prognostic power of peak oxygen uptake for heart failure patients.

BACKGROUND Peak oxygen uptake (V̇O2) and ventilatory efficiency (V̇E/V̇CO2slope) measured on cardiopulmonary exercise testing (CPX) are prognostic indicators in heart failure (HF) patients, but peak V̇O2is influenced by patient effort. In CPX targeting a peak respiratory exchange ratio (pRER; an objective index of effort adequacy) higher than the commonly recommended level, we assessed the safety a...

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Effects of respiratory exchange ratio on the prognostic value of peak oxygen consumption and ventilatory efficiency in patients with systolic heart failure.

OBJECTIVES The purpose of this analysis was to evaluate the prognostic characteristics of peak oxygen consumption (Vo2) and the minute ventilation/carbon dioxide (VE/Vco2) slope of different peak respiratory exchange ratios (RERs) obtained from cardiopulmonary exercise testing in patients with heart failure (HF). BACKGROUND For patients with HF, peak Vo2 and the VE/Vco2 slope are used for ass...

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Comparison of the long-term prognostic value of peak exercise oxygen pulse and peak oxygen uptake in patients with chronic heart failure.

OBJECTIVE To evaluate the ratio of peak oxygen consumption to peak heart rate (peak oxygen pulse) as a predictor of long term prognosis in chronic heart failure. PATIENTS AND SETTING 178 consecutive heart failure patients recruited to the cardiology department of a tertiary referral centre between 1986 and 1993. DESIGN Bicycle ergometry with measurement of respiratory exchange. Mean (SD) fo...

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Combining peak oxygen consumption and ventilatory efficiency in the prognostic assessment of patients with heart failure.

Exercise ventilatory efficiency (VE/VCO2 slope) and peak oxygen consumption (VO2) are strong mortality predictors in patients with heart failure and we combined these 2 variables' beta coefficients from Cox regression to investigate a new prognostic index. Average follow-up was 3.8+/-1.8 years for 355 patients (72% male, 51+/-10 years). The beta coefficients from peak VO2 (17.3+/-5.0 ml x kg(-1...

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The Prognostic Value of Peak Cardiac Power Output in Chinese Patients with Chronic Heart Failure

BACKGROUND Cardiopulmonary exercise testing has been widely used to risk stratify patients with chronic heart failure (CHF). Peak oxygen consumption (peakVO2) was regarded as a powerful predictor of survival, as it is a surrogate for peak cardiac output (CO), which by most is considered the "true" measure of heart failure. Therefore, it is reasonable to hypothesize that CO is an even stronger p...

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ژورنال

عنوان ژورنال: Circulation Journal

سال: 2014

ISSN: 1346-9843,1347-4820

DOI: 10.1253/circj.cj-14-0047